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Weight loss and Alzheimer’s disease

Weight loss is a common phenomenon during Alzheimer’s disease, which even occurs before the first symptoms become visible. Weight loss and subsequently, malnutrition cause complications, such as fall-related incidents which quickly aggravate the patient’s health condition and which eventually might result in the patient’s death. The causes of this weight loss are hardly known and several factors play a role.

The use of Mirtazapine, an anti-depressant arising appetite, is a drug used in the fight against Alzheimer’s Disease. In the framework of a study, we have been able to demonstrate that the use of this drug caused a weight increase among 80% of the patients and that this situation still persisted after a treatment of 6 months.

We now propose to carry out large prospection to determine the optimal dose of this drug, its safety, as well as potential profits in terms of objective, nutritional parameters.

Project coordination

>Prof. Murielle Surquin

Prof. Murielle Surquin
Weight loss and Alzheimer’s disease